Serotype Specific Sequence for Multi Test Line Nucleic Acid Lateral Flow Development

Sensitivity and Specificity of Nucleic Acid Sequence-Based Amplification Method for Diagnosis of Cutaneous Leishmaniasis

Abstract Background and Objective: Culture, microscopic method is a gold standard method for identification of Lishmania parasite. The use of Molecular methods such as RT- PCR compared to microscopic methods has a higher sensitivity and specificity however, it is not widely used due to its expensive equipment and the time requested. The use of nucleic acid sequence based amplification (NASBA) ...

Nucleic acid sequence citations: need for more-specific guidelines.

It is a policy of the Journal ofClinical Microbiology (JCM) and other ASM journals to encourage prompt submission of nucleic acid sequences to GenBank/EMBL. As stated in the Instructions to Authors, "It is expected that GenBank/ EMBL accession numbers for primary nucleotide and/or amino acid sequence data will be included in the original manuscript or be inserted when the manuscript is modified...

Development of Artificial Lateral-line Flow Sensors

Evolved over hundreds of millions of years, many fish species rely on lateral line sensors to monitor surrounding flow fields for maneuvering and survival under water [1]. It is conjectured that fish is equipped with distance touch sense of underwater obstacles, predators, and prey. A lateral line system, shown in Fig. 1, consists of an array of distributed sensor nodes (so called neuromasts) t...

Development of a Novel Lateral-Flow Assay to Detect Yeast Nucleic Acid Sequences

Sequence-Specific Nucleic Acid Damage by Peptide Nucleic Acid Conjugates That Can Be

Inhibition of gene expression is of great interest to explore gene function or for therapeutic applications. Oligonucleotides that interact with a specific RNA (antisense strategy) or DNA (antigene strategy) sequence are very attractive to disrupt gene expression. Structural modifications brought to the last generation of oligonucleotides like PNAs (peptide nucleic acids) have led to molecules ...